Introduction
Biochemical analyzers are essential laboratory instruments used to analyze various biochemical parameters in biological samples.However, like any other complex equipment, they can experience occasional malfunctions.This article aims to highlight some common problems encountered with biochemical analyzers and provide precautionary measures to minimize the occurrence of such issues.
What Are The Common Malfunctions Of Biochemical Analyzers?
1.When the machine is turned on, the alarm will beep for a long time
In the machine settings, if the setting is to print with an external printer, you must turn on the printer first, and then turn on the host, so that the host can detect the printer during self-test, otherwise the machine will alarm; the sensor window is dirty or the sensitivity of the sensor is not enough Or malfunction, the window should be cleaned to eliminate the wrong sample injection signal, if the sensor fails, replace the infrared automatic sensor.
2.Turn on the machine and set it to zero display “measurement problem”
Use distilled water for zero adjustment, when the above problems occur, it is usually because:
(1). The distilled water is not clean.
(2). There are air bubbles in the flow colorimetric cell, check whether the pipeline is damaged or whether the colorimetric cell leaks.
(3). If the inside of the mobile colorimetric cell is too dirty, soak it in 5% sodium hypochlorite for half an hour and then rinse it; if there is too much dust outside the mobile colorimetric cell, you should wipe it with lens tissue.
(4). The power supply of the quartz halogen lamp is taken out from the power switch. The power switch has three sets of connectors. One line supplies power to the host, one line is the power ground, and the other set supplies power to the lamp. Test that the set of joints is not conducting, remove and check Connector spring and power switch.
(5). Remove the optical filter, remove the glue with tweezers, take out the convex lens, install it on the machine, reset to zero, and troubleshoot.
(6). Even if the above work is done, the zero adjustment still fails. Remove the base of the colorimetric cell heater, open the cover of the silicon photodiode detection system, adjust the optical path, turn off the indoor light, place a piece of white paper on the front of the silicon photodiode, and move the colorimetric cell heater left and right At the same time, adjust the height adjustment screw under the colorimetric cell to carry out the zero adjustment operation. When the light is on, observe whether the light from the light is consistent with the position of the silicon photodiode, and adjust repeatedly until the zero adjustment is passed. Restart the zero adjustment , the above-mentioned fault still occurs. After careful observation, it is found that there is hot melt on the bottom of the heater base of the colorimetric cell. Hot melt, reinstalled for zero adjustment, and the fault disappeared.
3.After pressing the sample suction switch, the sample will not be sucked
First observe whether the pump is working, if not, check whether there is a signal from the suction switch, adjust the position of the top bead in the suction switch, and check whether the internal resistance of the pump is normal; secondly, check whether there is leakage or aging of the pump management, and then replace the pump If the above parts are normal, open the top cover of the machine and remove the flow colorimetric cell. If there is leakage in the flow colorimetric cell, use acid and alkali resistant, colorless adhesive for bonding, and wait for the adhesive to solidify , reinstall the flow cell.
4.The machine measurement result is incorrect
First use the following recommended cleaning agents to clean the flow cell and pipeline, and then test the standard tube. If the result is still incorrect, start the machine and check whether the heating block in the electronic temperature controller has voltage, whether the voltage is normal, and the power cord. Whether the connection is good or not, two different states of heating and cooling are produced by controlling the direction of the current flowing through the electronic components. When the current is forward, it is heating, and when it is reversed, it is cooling. If the heating block is damaged, replace the heating block. Pay attention when replacing Its directionality ensures that the heating block is in a heating state when the positive pressure is applied, otherwise the heating block may be burned; it may also be that the bulb is aging, and the bulb needs to be replaced, and the position of the bulb needs to be adjusted after replacement. For the specific adjustment method, refer to the machine manual, check The thermistor at the bottom of the flow colorimetric cell, the performance reduction or damage of the thermistor may also cause abnormal temperature control, thus affecting the correctness of the test results.
5.The printer does not print
First check whether the printing motor is normal, and then follow the cable to check whether the motor driver integrated circuit has a driving voltage when printing, if not, replace the motor driver integrated circuit, check whether the motor driver integrated circuit has a power supply voltage, if not, check the power circuit, The power supply voltage is normal. It is found that there is a drive triode between the power supply voltage stabilization block and the motor drive integrated circuit power supply. After testing the triode, it is found that there is a short circuit between electrodes. Replace the triode and restart the printer to print.
What Precautions Should Be Taken When Using Biochemical Analyzers?
1.The biochemical analyzer should be equipped with an electronic AC voltage stabilizer to prevent the measurement results from being affected or damage to the instrument due to power fluctuations. In addition, the instrument must have good grounding.
2.The working room of the biochemical analyzer is far away from electromagnetic fields and X-ray sources. It should be dust-free and dry, and the ambient temperature should be kept in the range of (15-30)℃.
3.Do not switch on and off the biochemical analyzer frequently in a short period of time. The continuous operation of the instrument generally does not exceed 4 hours.
4.If the biochemical analyzer is not used for a long time, it is necessary to ensure that it is turned on once every half a month, 4 hours each time, so as to charge the battery in the instrument and remove the moisture in the circuit at the same time.
5.The printer needs to replace with new printing paper before the paper roll is almost used up, so as to prevent the printer from running out of paper and prevent the rubber tire from wearing the printing sheet.
6.Rinse with distilled water after turning on the machine every day, which is conducive to pipe cleaning and sample zeroing.
7.When encountering an item that has a standard measurement, the standard should be used as a sample to measure again, so that the accuracy of the result can be judged according to the standard value.
8.When the samples are added to the machine for measurement, they should be arranged according to the reaction color from light to dark. After each sample is completed, distilled water should be used as a sample before making the next sample, which can prevent cross-contamination from affecting the results.
Conclusion
Biochemical analyzers play a crucial role in laboratory diagnostics and research.Understanding and addressing common malfunctions encountered in these analyzers is essential for ensuring accurate and reliable results.By following proper troubleshooting steps and seeking technical support when necessary, laboratory personnel can minimize downtime and maintain the performance of their biochemical analyzers.By following the precautions outlined in this article, laboratory personnel can ensure the accuracy and reliability of their biochemical analyses while maintaining a safe working environment.
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