Introduction
Immunoassay analyzers are essential tools in medical laboratories for detecting and measuring substances of interest, such as hormones, proteins, and antibodies, in various biological samples. However, like any complex instrument, these analyzers can experience malfunctions that may hinder accurate results and data integrity. This article discusses some common malfunctions encountered with immunoassay analyzers and provides essential precautions to ensure reliable and consistent performance.
What Are The Common Malfunctions Of Immunoassay Analyzers?
1.The pressure gauge indicates zero: Carry out a vacuum pressure test. At this time, the working sound of the pump should be heard, but the pressure gauge indicates zero. First check the vacuum tube connected to the waste liquid bottle, test the vacuum pressure, and determine whether the fault is caused by an air leak or a damaged pressure gauge. Check whether there is any air leakage at the interface of each pipeline, check the relevant solenoid valve (during the vacuum pressure test, the solenoid valve does not work and is in the closed state), and repair or replace the problematic pipeline or solenoid valve in time.
2.Insufficient vacuum pressure: Carry out a vacuum pressure test. If the test result is normal, it is known that the vacuum sensor cannot detect the vacuum pressure. The pressure test of this machine uses two sensors to detect high and low pressure respectively. After adjusting or cleaning the problematic sensor, test the vacuum pressure again. After the pressure is normal, adjust the sensor screw to make the high and low pressure indications within the specified range.
3.Luminous body error: Check the surface of the luminous body and find that there is liquid leakage. The fault is checked in three steps: check whether the waste liquid probe, related pipelines and cleaning pool are blocked or leaking; Solenoid valve, solenoid valve, if there is dirt, it will cause poor water intake or drainage; check whether there is air leakage in the cleaning pipeline of the alkali pump connected to the pipeline of the waste liquid probe and whether there are cracks in the alkali pump.
4.Track error: This fault is caused by the dislocation of the specimen holder in the track and the track cannot run. Because the track is long and airtight and not easy to disassemble, generally check the horizontal elevator connected to the track first. If it is normal, check the track again. Take out the misplaced specimen holder, and the fault can be eliminated.
What Precautions Should Be Taken When Using Immunoassay Analyzers?
1.The instrument should be used in a level, stable and clean environment. Air dust and smog contain rare earth ions to varying degrees, especially in northern regions. Therefore, a relatively dust-free operating environment should be established to prevent equipment from , Reagents and operators may cause pollution due to careless operation.
2.During the operation, follow the laboratory safety work rules, wear gloves and work clothes, and do not wear jewelry to avoid potential dangers; in the experiment, you should pay attention to the safety of electricity use and do not touch live parts; the handling of specimens and other wastes should comply with the experimental regulations. Comply with the relevant regulations of the laboratory and pay attention to biological safety.
3.Strictly abide by the operating procedures during use. If the instrument fails, report it to the person in charge of management or the person in charge of the department immediately, find out the cause, and deal with it in a timely manner. Do not “repair” without authorization, and register the “Registration of Instrument and Equipment Use”.
4.Avoid adding air bubbles or inhaling clots when adding samples.
5.Markers are the key to improving sensitivity and reducing non-specific binding. Due to the influence of labeling method, antibody concentration, quality of rare earth elements or their chelates and heterogeneity in labeling, the quality of each batch of markers has certain differences. , so different batches of markers have different sensitivities and cannot be mixed, and a standard curve is required for each determination.
6.Most of the current immune analyzers are extremely sensitive, and many factors can affect their accuracy. Therefore, each step of the operation should be strictly followed the operating procedures.
Conclusion
Immunoassay analyzers play a critical role in modern medical diagnostics, but their reliability hinges on proper operation and maintenance. By being aware of common malfunctions and following precautions, laboratories can ensure consistent, accurate, and trustworthy results. Regular training, adherence to protocols, and vigilance in quality control are essential to maintaining the integrity of immunoassay analysis in clinical practice.
Why Choose Us?
CNMEDITECH is dedicated to the long-term research of the immune analyzer market. Our mission is “People oriented and win-win strategy,Matching the real needs of the region with a focus on human health,To be the world’s first-class medical field solution expert”. We have been manufacturing high-quality medical device products for more than ten years.
We have built our reputation on delivering quality healthcare solutions on time and on budget. All our products comply with international health and safety regulations and all products come with a warranty.
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