The electrolyte analyzer is indispensable in clinical testing. In clinical testing, it mainly tests and maintains human blood. The balance of osmotic pressure in body fluids, ion testing and detection is very important in patients who require large amounts of balanced fluid rehydration such as surgery, burns, diarrhea, acute myocardial infarction, etc. The instrument has high precision and accuracy. The results measured on any sample are accurate, reliable, fast, and the operation is very simple. Therefore, ion detection is a necessary general equipment for hospitals at all levels.
Electrolyte analyzers use ion-selective electrode measurement methods to achieve accurate detection. There are six types of electrodes on the instrument: sodium, potassium, chloride, ionized calcium, lithium and reference electrode. Each electrode has an ion-selective membrane that reacts with the corresponding ions in the sample to be measured. The membrane is an ion exchanger that reacts with the ion charge to change the membrane potential, and the potential between the liquid, sample, and membrane can be detected.The two potential differences detected on both sides of the membrane will generate a current. The sample, reference electrode, and reference electrode liquid form one side of the “loop”; the membrane, internal electrode liquid, and internal electrode are the other side.
The difference in ion concentration between the internal electrode solution and the sample generates an electrochemical voltage across the membrane of the working electrode. The voltage is led to the amplifier through the highly conductive internal electrode. The reference electrode is also led to the location of the amplifier. The ion concentration in the sample is measured by detecting a precise standard solution of known ion concentration to obtain a calibration curve.
When the measured ions in the solution contact the electrode, ion migration occurs within the aqueous layer of the ion-selective electrode matrix. There is a potential due to the charge change of the migrating ions, which causes the potential between the membrane surfaces to change, creating a potential difference between the measuring electrode and the reference electrode. Ion-selective electrode. The electrode contains an electrode solution with a known ion concentration. Through the ion-selective electrode membrane, it interpenetrates with the corresponding ions in the sample, thereby generating a membrane potential on both sides of the membrane. Different ion concentrations in the sample will produce a different potential signal. Differently, the concentration of ions in the sample can be measured by measuring the potential signal size.
The difference in ion concentration between the liquid in the electrode and the sample causes the electrode membrane to generate an electrochemical potential. This potential can be taken out by the electrode and sent to the input end of the amplifier. The other input end of the amplifier is connected to the reference electrode and grounded, and the electrode voltage can be further amplified. The voltage difference formed determines the ion concentration of the sample being measured.
When the measured ions in the electrode solution contact the electrode, ion migration occurs within the aqueous layer of the ion-selective electrode membrane matrix. There is an electric potential when the charge of migrating ions changes, thus causing the electric potential between the membrane surfaces to change; a potential difference is generated between the measuring electrode and the reference electrode. The potential difference generated by an ideal ion-selective electrode for the ions to be measured in the solution should conform to the Nernst equation: E=E0+ log10a(x) E: (E0: standard electrode potential (constant); R: gas Constant; T: absolute temperature; Z: ion valence; F: Faraday’s constant; a(x): activity of ion)
When using an electrolyte analyzer, first turn on the instrument and enter the system self-check to check whether the main components are functioning normally, such as: instrument main board, printer, liquid line detection (completed by liquid detector), distribution valve and valve detector, etc. It can intelligently identify and judge faults and automatically prompt; enter the activation electrode program, and has an electrode activation timing function to accurately grasp the activation time to increase the service life of the electrode and ensure electrode stability. The time is 30 minutes countdown. You can press the NO key to exit the activation electrode program directly; enter the main menu, first perform system calibration, and automatically select the base point and slope calibration; select quality control analysis, and after more than 5 quality control tests , can automatically generate and print quality control reports, and calculate the average, standard deviation, and coefficient of variation of the number of quality controls performed. Testable samples include: whole blood, serum, plasma, urine, body fluids, cerebrospinal fluid, urine, animal serum, etc. Measurement method: ion selective electrode (ISE) direct method. Test items include: K+, Na+, Cl-, Ca++, PH, CO2.
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CNMEDITECH is dedicated to the long-term research of the electrolyte analyzer market. Our mission is “People oriented and win-win strategy,Matching the real needs of the region with a focus on human health,To be the world’s first-class medical field solution expert”. We have been manufacturing high-quality medical device products for more than ten years.
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